Description
Hba-x, also known as Hemoglobin subunit zeta (Hbz), is belongs to the globin family. Zeta-globin is alpha-like hemoglobin. The Hba-x polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. Hba-x gene includes five functional genes and two pseudogenes. The order of genes is: 5' -zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. Recombinant mouse Hba-x fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques